Hyaluronic acid is the most common glycosaminoglycan in the skin and, when injected, it promotes growth, softening and hydration through powerful links with water. Concurrent localized scleroderma and discoid lupus erythematosus. A rare type of localized scleroderma can lead to Romberg's disease which represents an arrest of bone growth which leads to facial hemiatrophy. It is necessary to make a differential diagnosis between primary and secondary RP in order to guide management, taking into account that the primary form is considered a benign pathology that can show significant improvements with topical and lifestyle changes Table 2. Withdrawal from nitrates should be gradual.
What you need to know about scleroderma
Photochemotherapy using psoralenes and UVA PUVA causes apoptosis of the T cells infiltrating the skin and for many years has been shown to have highly beneficial effect on some disorders, such as psoriasis, atopic dermatitis and T-cell cutaneous lymphoma. Examples include silica, epoxy resins and welding fumes. Mouth dryness is subjectively one of the most troublesome attaints in the facial region of SSc. Localized scleroderma: a clinical study of two hundred thirty-five cases. The ACA anti-centromere antibody is considered a marker of the CREST syndrome, characterized by calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasias.
Classification of Scleroderma | Localized, Systemic
Research has shown that patients with systemic scleroderma have a higher risk of atherosclerosis than healthy individuals. Naturally the rarity of the SSc also hampers further research. The main surgical management options are chemical or surgical, cervical, thoracic or ultra-selective digital sympathectomy, which can be considered as emergency measures to achieve rapid vasodilation. This can be harmful for people with an auto-immune disease. Morphea and Localized Scleroderma in Children. Decreased salivary flow can create problems for patients who are completely or partially edentulous. Late in the disease, a resorption in the end of the distal phalanges of the fingers can occur as result of lack of vascular supply.
No patient has been found to have both. It can affect bones and muscles. The number eosinophils and erythrocyte sedimentation rate ESR are found to be increased in case of disease activity or relapse. In these cases, oral corticosteroids are the first choice. Share on: Facebook Twitter. The goal of treatment is to control the symptoms, although the disease usually develops into heart failure. However, this is a very rare occurrence in childhood.